Recently, Associate Professor Kong Dezhao of the School of w88 online casino betting Science and Technology of our school(First corresponding author) with Jiangsu University of Science and Technology as the first unitJournal of Agricultural and w88 online casino betting ChemistryPostedResearch paper“Enzyme-Assisted Solid-Phase Microextraction Coupled with DNA Nanowalker for Dual-Amplified Detection of Chloramphenicol in Animal-Derived w88 online casino betting Products”。Journal of Agricultural and w88 online casino betting Chemistry(TOP of District 1, Chinese Academy of Sciences,IF=5.7) is a top international journal in the fields of agricultural and w88 online casino betting chemistry and biochemistry。The first author of this paper is the School of Environmental and Chemical Engineering2020Master’s student Chen Yitong,Professor Li Xianji of the School of Environmental and Chemical Engineering and Professor Tang Sheng of the Academy of SciencesforUnitedCorresponding author。
Various antibiotics widely used in agriculture, forestry and animal husbandry have become one of the main sources of w88 online casino betting contamination,In particular, the bioaccumulation effect of trace residues poses a more hidden threat to the human body。Therefore, it is particularly important to accurately and conveniently analyze trace antibiotic residues in complex w88 online casino betting samples。The researcher’s team uses original quartz rod nucleic acid modification technology to construct a solid-phase microextraction system,CombinedDNANano walker probe,Ultra-sensitive detection of chloramphenicol through dual amplification strategy。In addition,Through administration experiments on living animals,Explored the accumulation phenomenon of trace amounts of chloramphenicol in organisms。
In this research strategy,Constructing a solid-phase microextraction system using quartz rods with surface-modified nucleic acid sequencesAnalyteidentification capture, condensedEnrichedandDetectionIntroduction processCollectionforOne body,Greatly simplifies sample preprocessing operations;By quartz rod matrix andDNAThe interaction between the enzyme cycle shearing system will affect the effect of chloramphenicolDetection converted tofor specificnucleic acidSerialDetection,And perform the first nucleic acid sequence amplification;By the fourth generation sensor—DNAOperation of isothermal nucleic acid amplification on the surface of walker nanoparticles,w88 online casino betting was amplified for the second time。
This solution significantly reduces w88 online casino betting matrix interference during the detection process,And through the conversion and amplification of the target and specific nucleic acid sequences,Greatly improved the detection signal,Provides a practical basis for effective monitoring of trace targets in real samples。
In recent years,The team leverages related technologies,Published multiple relevant papers in top international publications in the w88 online casino betting field,such asw88 online casino betting Chem., 2024, 442, 138505;w88 online casino betting Chem., 2023, 416, 135856;Anal. Chem., 2022, 94, 10595-10600;w88 online casino betting Control, 2025, 168, 110871etc.,Solved the problem of highly sensitive detection of hazardous substances in w88 online casino betting。Relevant research received the National Natural Science Foundation of China、Jiangsu Provincial Natural Science Foundation、Support from Jiangsu University of Science and Technology’s “Deep Blue Talent Project” training object funding project。